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A fluorescent metal-sensor study provides evidence for iron transport by transcytosis in the intestinal epithelial cells

Iron transport across the intestinal epithelium is facilitated by the divalent metal transporter 1 (DMT1) on the brush border membrane (BBM). The fluorescent metal sensor calcein, which is hydrophilic, membrane-impermeable and quenched by chelation with iron, was used to test our hypothesis that int...

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Detalles Bibliográficos
Autores principales: Ma, Yuxiang, Okazaki, Yasumasa, Glass, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773836/
https://www.ncbi.nlm.nih.gov/pubmed/29362518
http://dx.doi.org/10.3164/jcbn.17-74