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Computational identification of harmful mutation regions to the activity of transposable elements

BACKGROUND: Transposable elements (TEs) are interspersed DNA sequences that can move or copy to new positions within a genome. TEs are believed to promote speciation and their activities play a significant role in human disease. In the human genome, the 22 AluY and 6 AluS TE subfamilies have been th...

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Detalles Bibliográficos
Autores principales: Jin, Lingling, McQuillan, Ian, Li, Longhai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773891/
https://www.ncbi.nlm.nih.gov/pubmed/29219079
http://dx.doi.org/10.1186/s12864-017-4227-z