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RNA‐Peptide nanoplexes drug DNA damage pathways in high‐grade serous ovarian tumors

DNA damaging chemotherapy is a cornerstone of current front‐line treatments for advanced ovarian cancer (OC). Despite the fact that a majority of these patients initially respond to therapy, most will relapse with chemo‐resistant disease; therefore, adjuvant treatments that synergize with DNA‐damagi...

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Detalles Bibliográficos
Autores principales: Dreaden, Erik C., Kong, Yi Wen, Quadir, Mohiuddin A., Correa, Santiago, Suárez‐López, Lucia, Barberio, Antonio E., Hwang, Mun Kyung, Shi, Aria C., Oberlton, Benjamin, Gallagher, Paige N., Shopsowitz, Kevin E., Elias, Kevin M., Yaffe, Michael B., Hammond, Paula T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773954/
https://www.ncbi.nlm.nih.gov/pubmed/29376131
http://dx.doi.org/10.1002/btm2.10086