Calpain‐2 inhibitor treatment preferentially reduces tumor progression for human colon cancer cells expressing highest levels of this enzyme

Calpain‐2 levels are higher in colorectal tumors resistant to chemotherapy and previous work showed calpain‐2 inhibitor therapy reduced inflammation‐driven colorectal cancer, but direct effects of the inhibitor on colon cancer cells themselves were not demonstrated. In the present study, five human...

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Detalles Bibliográficos
Autores principales: Marciel, Michael P., Rose, Aaron H., Martinez, Verena, Horio, David T., Hashimoto, Ann S., Hoffmann, FuKun W., Bertino, Pietro, Hoffmann, Peter R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773958/
https://www.ncbi.nlm.nih.gov/pubmed/29210197
http://dx.doi.org/10.1002/cam4.1260

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773958/
https://www.ncbi.nlm.nih.gov/pubmed/29210197
http://dx.doi.org/10.1002/cam4.1260

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