Towards functional selectivity for α6β3γ2 GABA(A) receptors: a series of novel pyrazoloquinolinones

BACKGROUND AND PURPOSE: The GABA(A) receptors are ligand‐gated ion channels, which play an important role in neurotransmission. Their variety of binding sites serves as an appealing target for many clinically relevant drugs. Here, we explored the functional selectivity of modulatory effects at speci...

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Detalles Bibliográficos
Autores principales: Treven, Marco, Siebert, David C B, Holzinger, Raphael, Bampali, Konstantina, Fabjan, Jure, Varagic, Zdravko, Wimmer, Laurin, Steudle, Friederike, Scholze, Petra, Schnürch, Michael, Mihovilovic, Marko D, Ernst, Margot
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773961/
https://www.ncbi.nlm.nih.gov/pubmed/29127702
http://dx.doi.org/10.1111/bph.14087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773961/
https://www.ncbi.nlm.nih.gov/pubmed/29127702
http://dx.doi.org/10.1111/bph.14087

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