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Towards functional selectivity for α6β3γ2 GABA(A) receptors: a series of novel pyrazoloquinolinones
BACKGROUND AND PURPOSE: The GABA(A) receptors are ligand‐gated ion channels, which play an important role in neurotransmission. Their variety of binding sites serves as an appealing target for many clinically relevant drugs. Here, we explored the functional selectivity of modulatory effects at speci...
Autores principales: | Treven, Marco, Siebert, David C B, Holzinger, Raphael, Bampali, Konstantina, Fabjan, Jure, Varagic, Zdravko, Wimmer, Laurin, Steudle, Friederike, Scholze, Petra, Schnürch, Michael, Mihovilovic, Marko D, Ernst, Margot |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773961/ https://www.ncbi.nlm.nih.gov/pubmed/29127702 http://dx.doi.org/10.1111/bph.14087 |
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