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SMG‐1 inhibition by miR‐192/‐215 causes epithelial‐mesenchymal transition in gastric carcinogenesis via activation of Wnt signaling

SMG‐1,a member of the phosphoinositide kinase‐like kinase family, functioned as a tumor suppressor gene. However, the role of SMG‐1 in GC remain uncharacterized. In this study, regulation of SMG‐1 by miR‐192 and‐215, along with the biological effects of this modulation, were studied in GC. We used g...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaojing, Peng, Yin, Huang, Yong, Yang, Mengting, Yan, Ruibin, Zhao, Yanqiu, Cheng, Yulan, Liu, Xi, Deng, Shiqi, Feng, Xianling, Lin, Huijuan, Yu, Huimin, Chen, Si, Zhao, Zhenfu, Li, Shanni, Li, Kuan, Wang, Liang, Wei, Yanjie, He, Zhendan, Fan, Xinmin, Meltzer, Stephen J., Li, Song, Jin, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773975/
https://www.ncbi.nlm.nih.gov/pubmed/29239144
http://dx.doi.org/10.1002/cam4.1237