Radiation-induced pulmonary gene expression changes are attenuated by the CTGF antibody Pamrevlumab

BACKGROUND: Fibrosis is a delayed side effect of radiation therapy (RT). Connective tissue growth factor (CTGF) promotes the development of fibrosis in multiple settings, including pulmonary radiation injury. METHODS: To better understand the cellular interactions involved in RT-induced lung injury...

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Detalles Bibliográficos
Autores principales: Sternlicht, Mark D., Wirkner, Ute, Bickelhaupt, Sebastian, Lopez Perez, Ramon, Tietz, Alexandra, Lipson, Kenneth E., Seeley, Todd W., Huber, Peter E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774112/
https://www.ncbi.nlm.nih.gov/pubmed/29347981
http://dx.doi.org/10.1186/s12931-018-0720-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774112/
https://www.ncbi.nlm.nih.gov/pubmed/29347981
http://dx.doi.org/10.1186/s12931-018-0720-4

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