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Radiation-induced pulmonary gene expression changes are attenuated by the CTGF antibody Pamrevlumab
BACKGROUND: Fibrosis is a delayed side effect of radiation therapy (RT). Connective tissue growth factor (CTGF) promotes the development of fibrosis in multiple settings, including pulmonary radiation injury. METHODS: To better understand the cellular interactions involved in RT-induced lung injury...
Autores principales: | Sternlicht, Mark D., Wirkner, Ute, Bickelhaupt, Sebastian, Lopez Perez, Ramon, Tietz, Alexandra, Lipson, Kenneth E., Seeley, Todd W., Huber, Peter E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774112/ https://www.ncbi.nlm.nih.gov/pubmed/29347981 http://dx.doi.org/10.1186/s12931-018-0720-4 |
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