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Chromothripsis 18 in multiple myeloma patient with rapid extramedullary relapse

BACKGROUND: Catastrophic chromosomal event known as chromothripsis was proven to be a significant hallmark of poor prognosis in several cancer diseases. While this phenomenon is very rare in among multiple myeloma (MM) patients, its presence in karyotype is associated with very poor prognosis. CASE...

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Detalles Bibliográficos
Autores principales: Smetana, Jan, Oppelt, Jan, Štork, Martin, Pour, Luděk, Kuglík, Petr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774134/
https://www.ncbi.nlm.nih.gov/pubmed/29375670
http://dx.doi.org/10.1186/s13039-018-0357-5