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FMS-Like Tyrosine Kinase 3 (FLT3) and Nucleophosmin 1 (NPM1) in Iranian Adult Acute Myeloid Leukemia Patients with Normal Karyotypes: Mutation Status and Clinical and Laboratory Characteristics

OBJECTIVE: In this study, we evaluated the frequency of FMS-like tyrosine kinase 3 (FLT3-ITD and FLT3-TKD) and nucleophosmin (NPM1) mutations in Iranian patients with cytogenetically normal acute myeloid leukemia (CN-AML). The clinical and laboratory characteristics were compared between wild-type a...

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Detalles Bibliográficos
Autores principales: Rezaei, Narges, Arandi, Nargess, Valibeigi, Behnaz, Haghpanah, Sezaneh, Khansalar, Mehdi, Ramzi, Mani
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774351/
https://www.ncbi.nlm.nih.gov/pubmed/28294102
http://dx.doi.org/10.4274/tjh.2016.0489