Analysis of an ATP-induced conformational transition of ABC transporter MsbA using a coarse-grained model

Upon the binding of ATP molecules to nucleotide binding domains (NBDs), ATP-binding cassette (ABC) exporters undergo a conformational transition from an inward-facing (IF) to an outward-facing (OF) state. This molecular event is a typical example of chemo-mechanical coupling. However, the underlying...

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Detalles Bibliográficos
Autores principales: Arai, Naoki, Furuta, Tadaomi, Sakurai, Minoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society of Japan (BSJ) 2017
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774416/
https://www.ncbi.nlm.nih.gov/pubmed/29362701
http://dx.doi.org/10.2142/biophysico.14.0_161

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774416/
https://www.ncbi.nlm.nih.gov/pubmed/29362701
http://dx.doi.org/10.2142/biophysico.14.0_161

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