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BmK CT enhances the sensitivity of temozolomide-induced apoptosis of malignant glioma U251 cells in vitro through blocking the AKT signaling pathway

Temozolomide (TMZ) is a drug that has been demonstrated to improve the survival time of patients with glioblastoma multiforme (GBM) when administered with concomitant radiotherapy. However, chemoresistance is one of the major obstacles in the treatment of GBM. In the present study, an MTT assay and...

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Detalles Bibliográficos
Autores principales: Du, Jun, Wang, Ruijie, Yin, Litian, Fu, Yuejun, Cai, Yuqing, Zhang, Zhiyun, Liang, Aihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774446/
https://www.ncbi.nlm.nih.gov/pubmed/29434848
http://dx.doi.org/10.3892/ol.2017.7483