Diminishing the side effect of mitomycin C by using pH-sensitive liposomes: in vitro characterization and in vivo pharmacokinetics

INTRODUCTION: Mitomycin C is an anticancer antibiotic agent that has the potential for broad-spectrum use against several cancers, including mammary cancers. Because its half-life is 17 min after a 30 mg intravenous bolus administration, the suitability of mitomycin C for wide use in the clinical se...

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Detalles Bibliográficos
Autores principales: Fang, Yi-Ping, Hu, Pei-Yu, Huang, Yaw-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774480/
https://www.ncbi.nlm.nih.gov/pubmed/29391780
http://dx.doi.org/10.2147/DDDT.S150201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774480/
https://www.ncbi.nlm.nih.gov/pubmed/29391780
http://dx.doi.org/10.2147/DDDT.S150201

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