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Characterization of the T-cell receptor repertoire by deep T cell receptor sequencing in tissues from patients with prostate cancer

Prostate cancer (PC) is the most prevalent urological cancer in men. T cells serve a central role in the cancer's immunological microenvironment. In the present study, we applied multiplex PCR and Illumina next-generation sequencing to study the clonal diversity of the T-cell receptor (TCR) rep...

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Detalles Bibliográficos
Autores principales: Liu, Song, Pan, Weibing, Cheng, Zhiqiang, Sun, Guoping, Zhu, Peng, Chan, Franky, Hu, Yunlong, Zhang, Xinzhou, Dai, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774533/
https://www.ncbi.nlm.nih.gov/pubmed/29399194
http://dx.doi.org/10.3892/ol.2017.7479