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Epidermal growth factor receptor aptamer-conjugated polymer-lipid hybrid nanoparticles enhance salinomycin delivery to osteosarcoma and cancer stem cells

Osteosarcoma is a common childhood bone cancer with a poor survival rate. Osteosarcoma cancer stem cells (CSCs) contribute to the recurrence, drug resistance and metastasis of this disease. Previous evidence suggested that cancer cells are able to spontaneously turn into CSCs, thus it is crucial to...

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Detalles Bibliográficos
Autores principales: Yu, Zuochong, Chen, Fangyi, Qi, Xiaoxia, Dong, Yinmei, Zhang, Yingying, Ge, Zhe, Cai, Guoping, Zhang, Xinchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774535/
https://www.ncbi.nlm.nih.gov/pubmed/29399118
http://dx.doi.org/10.3892/etm.2017.5578