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The Metal Coordination of sCD39 during ATP Hydrolysis

BACKGROUND: The hydrolysis of ATP and ADP by ecto-nucleoside triphosphate diphosphohydrolase 1 (CD39) requires divalent cations, like Ca(2+) and Mg(2+). In spite of considerable work, it is not clear whether divalent cations bind to the enzyme in the absence of nucleotide or only as nucleotide-Me(+2...

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Detalles Bibliográficos
Autores principales: Chen, Wei, Guidotti, Guido
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC57746/
https://www.ncbi.nlm.nih.gov/pubmed/11591225
http://dx.doi.org/10.1186/1471-2091-2-9