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Construction of an infectious horsepox virus vaccine from chemically synthesized DNA fragments

Edward Jenner and his contemporaries believed that his variolae vaccinae originated in horses and molecular analyses show that modern vaccinia virus (VACV) strains share common ancestry with horsepox virus (HPXV). Given concerns relating to the toxicity of modern VACV vaccines, we asked whether an H...

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Detalles Bibliográficos
Autores principales: Noyce, Ryan S., Lederman, Seth, Evans, David H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774680/
https://www.ncbi.nlm.nih.gov/pubmed/29351298
http://dx.doi.org/10.1371/journal.pone.0188453