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Construction of an infectious horsepox virus vaccine from chemically synthesized DNA fragments
Edward Jenner and his contemporaries believed that his variolae vaccinae originated in horses and molecular analyses show that modern vaccinia virus (VACV) strains share common ancestry with horsepox virus (HPXV). Given concerns relating to the toxicity of modern VACV vaccines, we asked whether an H...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774680/ https://www.ncbi.nlm.nih.gov/pubmed/29351298 http://dx.doi.org/10.1371/journal.pone.0188453 |