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Mutant loxP vectors for selectable marker recycle and conditional knock-outs

BACKGROUND: Gene disruption by targeted integration of transfected constructs becomes increasingly popular for studies of gene function. The chicken B cell line DT40 has been widely used as a model for gene knock-outs due to its high targeted integration activity. Disruption of multiple genes and co...

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Detalles Bibliográficos
Autores principales: Arakawa, Hiroshi, Lodygin, Dimitry, Buerstedde, Jean-Marie
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2001
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC57747/
https://www.ncbi.nlm.nih.gov/pubmed/11591226
http://dx.doi.org/10.1186/1472-6750-1-7