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Investigation of the proton relay system operative in human cystosolic aminopeptidase P

Aminopeptidase P, a metalloprotease, targets Xaa-Proline peptides for cleavage [1–4]. There are two forms of human AMPP, a membrane-bound form (hmAMPP) and a soluble cytosolic form (hcAMPP)[5]. Similar to the angiotensin-I-converting enzyme, AMPP plays an important role in the catabolism of inflamma...

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Detalles Bibliográficos
Autores principales: Chang, Hui-Chuan, Kung, Camy C.-H., Chang, Tzu-Ting, Jao, Shu-Chuan, Hsu, Yu-Ting, Li, Wen-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774706/
https://www.ncbi.nlm.nih.gov/pubmed/29351301
http://dx.doi.org/10.1371/journal.pone.0190816