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Methylglyoxal produces more changes in biochemical and biophysical properties of human IgG under high glucose compared to normal glucose level

Hyperglycaemia triggers increased production of methylglyoxal which can cause gross modification in proteins’ structure vis-a-vis function though advanced glycation end products (AGEs). The AGEs may initiate vascular and nonvascular pathologies. In this study, we have examined the biochemical and bi...

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Detalles Bibliográficos
Autores principales: Khan, Mohd Adnan, Arif, Zarina, Khan, Mohd Asad, Moinuddin, Alam, Khursheed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774746/
https://www.ncbi.nlm.nih.gov/pubmed/29351321
http://dx.doi.org/10.1371/journal.pone.0191014