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Methylglyoxal produces more changes in biochemical and biophysical properties of human IgG under high glucose compared to normal glucose level
Hyperglycaemia triggers increased production of methylglyoxal which can cause gross modification in proteins’ structure vis-a-vis function though advanced glycation end products (AGEs). The AGEs may initiate vascular and nonvascular pathologies. In this study, we have examined the biochemical and bi...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774746/ https://www.ncbi.nlm.nih.gov/pubmed/29351321 http://dx.doi.org/10.1371/journal.pone.0191014 |