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Whole thorax irradiation of non-human primates induces persistent nuclear damage and gene expression changes in peripheral blood cells

We investigated the cytogenetic and gene expression responses of peripheral blood cells of non-human primates (NHP, Macaca mulatta) that were whole-thorax irradiated with a single dose of 10 Gy. In this model, partial irradiation of NHPs in the thoracic region (Whole Thorax Lung Irradiation, WTLI) a...

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Detalles Bibliográficos
Autores principales: Ghandhi, Shanaz A., Turner, Helen C., Shuryak, Igor, Dugan, Gregory O., Bourland, J. Daniel, Olson, John D., Tooze, Janet A., Morton, Shad R., Batinic-Haberle, Ines, Cline, J. Mark, Amundson, Sally A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774773/
https://www.ncbi.nlm.nih.gov/pubmed/29351567
http://dx.doi.org/10.1371/journal.pone.0191402