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High-level production and purification in a functional state of an extrasynaptic gamma-aminobutyric acid type A receptor containing α4β3δ subunits

The inhibitory γ-aminobutyric acid type A receptors are implicated in numerous physiological processes, including cognition and inhibition of neurotransmission, rendering them important molecular targets for many classes of drugs. Functionally, the entire GABA(A)R family of receptors can be subdivid...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaojuan, Desai, Rooma, Zhang, Yinghui, Stec, Wojciech J., Miller, Keith W., Jounaidi, Youssef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774841/
https://www.ncbi.nlm.nih.gov/pubmed/29352320
http://dx.doi.org/10.1371/journal.pone.0191583