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Environmental stimuli shape microglial plasticity in glioma

In glioma, microglia and infiltrating macrophages are exposed to factors that force them to produce cytokines and chemokines, which contribute to tumor growth and to maintaining a pro-tumorigenic, immunosuppressed microenvironment. We demonstrate that housing glioma-bearing mice in enriched environm...

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Detalles Bibliográficos
Autores principales: Garofalo, Stefano, Porzia, Alessandra, Mainiero, Fabrizio, Di Angelantonio, Silvia, Cortese, Barbara, Basilico, Bernadette, Pagani, Francesca, Cignitti, Giorgio, Chece, Giuseppina, Maggio, Roberta, Tremblay, Marie-Eve, Savage, Julie, Bisht, Kanchan, Esposito, Vincenzo, Bernardini, Giovanni, Seyfried, Thomas, Mieczkowski, Jakub, Stepniak, Karolina, Kaminska, Bozena, Santoni, Angela, Limatola, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774898/
https://www.ncbi.nlm.nih.gov/pubmed/29286001
http://dx.doi.org/10.7554/eLife.33415