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DNA (cytosine-5)-methyltransferase 3B (DNMT 3B) polymorphism and risk of Down syndrome offspring

Down syndrome (DS) is the most common form of human genetic mental retardation. Several polymorphisms in genes coding folic acid cycle enzymes have been associated to the risk of bearing a DS child; however, the results are controversial. S-adenosyl-l-methionine (SAM) is an important intermediate of...

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Detalles Bibliográficos
Autores principales: Moura, Cláudia Melo de, Bastos, Pedro Ribeiro, Ribeiro, Julyana S.V., Ribeiro, Márcia Gonçalves, Amorim, Márcia Rodrigues, Costa-Lima, Marcelo Aguiar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775107/
https://www.ncbi.nlm.nih.gov/pubmed/29379364
http://dx.doi.org/10.1016/j.sjbs.2017.09.008