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Helicobacter pylori-Induced HB-EGF Upregulates Gastrin Expression via the EGF Receptor, C-Raf, Mek1, and Erk2 in the MAPK Pathway

Helicobacter pylori is associated with hypergastrinemia, which has been linked to the development of gastric diseases. Although the molecular mechanism is not fully understood, H. pylori is known to modulate the Erk pathway for induction of gastrin expression. Herein we found that an epidermal growt...

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Detalles Bibliográficos
Autores principales: Gunawardhana, Niluka, Jang, Sungil, Choi, Yun Hui, Hong, Youngmin A., Jeon, Yeong-Eui, Kim, Aeryun, Su, Hanfu, Kim, Ji-Hye, Yoo, Yun-Jung, Merrell, D. Scott, Kim, Jinmoon, Cha, Jeong-Heon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775237/
https://www.ncbi.nlm.nih.gov/pubmed/29379775
http://dx.doi.org/10.3389/fcimb.2017.00541