A urine-dependent human urothelial organoid offers a potential alternative to rodent models of infection

Murine models describe a defined host/pathogen interaction for urinary tract infection, but human cell studies are scant. Although recent human urothelial organoid models are promising, none demonstrate long-term tolerance to urine, the natural substrate of the tissue and of the uropathogens that li...

Descripción completa

Detalles Bibliográficos
Autores principales: Horsley, Harry, Dharmasena, Dhanuson, Malone-Lee, James, Rohn, Jennifer L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775255/
https://www.ncbi.nlm.nih.gov/pubmed/29352171
http://dx.doi.org/10.1038/s41598-018-19690-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775255/
https://www.ncbi.nlm.nih.gov/pubmed/29352171
http://dx.doi.org/10.1038/s41598-018-19690-7

Ejemplares similares