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A urine-dependent human urothelial organoid offers a potential alternative to rodent models of infection
Murine models describe a defined host/pathogen interaction for urinary tract infection, but human cell studies are scant. Although recent human urothelial organoid models are promising, none demonstrate long-term tolerance to urine, the natural substrate of the tissue and of the uropathogens that li...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775255/ https://www.ncbi.nlm.nih.gov/pubmed/29352171 http://dx.doi.org/10.1038/s41598-018-19690-7 |