Phosphorylation of the Transient Receptor Potential Ankyrin 1 by Cyclin-dependent Kinase 5 affects Chemo-nociception

Cyclin-dependent kinase 5 (Cdk5) is a key neuronal kinase that is upregulated during inflammation, and can subsequently modulate sensitivity to nociceptive stimuli. We conducted an in silico screen for Cdk5 phosphorylation sites within proteins whose expression was enriched in nociceptors and identi...

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Detalles Bibliográficos
Autores principales: Hall, Bradford E., Prochazkova, Michaela, Sapio, Matthew R., Minetos, Paul, Kurochkina, Natalya, Binukumar, B. K., Amin, Niranjana D., Terse, Anita, Joseph, John, Raithel, Stephen J., Mannes, Andrew J., Pant, Harish C., Chung, Man-Kyo, Iadarola, Michael J., Kulkarni, Ashok B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775258/
https://www.ncbi.nlm.nih.gov/pubmed/29352128
http://dx.doi.org/10.1038/s41598-018-19532-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775258/
https://www.ncbi.nlm.nih.gov/pubmed/29352128
http://dx.doi.org/10.1038/s41598-018-19532-6

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