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Chaski, a novel Drosophila lactate/pyruvate transporter required in glia cells for survival under nutritional stress

The intercellular transport of lactate is crucial for the astrocyte-to-neuron lactate shuttle (ANLS), a model of brain energetics according to which neurons are fueled by astrocytic lactate. In this study we show that the Drosophila chaski gene encodes a monocarboxylate transporter protein (MCT/SLC1...

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Detalles Bibliográficos
Autores principales: Delgado, María Graciela, Oliva, Carlos, López, Estefanía, Ibacache, Andrés, Galaz, Alex, Delgado, Ricardo, Barros, L. Felipe, Sierralta, Jimena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775259/
https://www.ncbi.nlm.nih.gov/pubmed/29352169
http://dx.doi.org/10.1038/s41598-018-19595-5