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Chaski, a novel Drosophila lactate/pyruvate transporter required in glia cells for survival under nutritional stress
The intercellular transport of lactate is crucial for the astrocyte-to-neuron lactate shuttle (ANLS), a model of brain energetics according to which neurons are fueled by astrocytic lactate. In this study we show that the Drosophila chaski gene encodes a monocarboxylate transporter protein (MCT/SLC1...
Autores principales: | Delgado, María Graciela, Oliva, Carlos, López, Estefanía, Ibacache, Andrés, Galaz, Alex, Delgado, Ricardo, Barros, L. Felipe, Sierralta, Jimena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775259/ https://www.ncbi.nlm.nih.gov/pubmed/29352169 http://dx.doi.org/10.1038/s41598-018-19595-5 |
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