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Plasma MCP-1 and Cognitive Decline in Patients with Alzheimer’s Disease and Mild Cognitive Impairment: A Two-year Follow-up Study

Monocyte chemoattractant protein-1 (MCP-1, also known as chemokine CCL2) is a vital chemokine that mediates inflammation in Alzheimer’s disease (AD). We analyzed the associations between the baseline plasma MCP-1 level, longitudinal cognitive changes, and genetic effects of CCL2 rs1024611 and its re...

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Detalles Bibliográficos
Autores principales: Lee, Wei-Ju, Liao, Yi-Chu, Wang, Yen-Feng, Lin, I-Feng, Wang, Shuu-Jiun, Fuh, Jong-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775300/
https://www.ncbi.nlm.nih.gov/pubmed/29352259
http://dx.doi.org/10.1038/s41598-018-19807-y