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Growth and remodeling play opposing roles during postnatal human heart valve development

Tissue growth and remodeling are known to govern mechanical homeostasis in biological tissue, but their relative contributions to homeostasis remain unclear. Here, we use mechanical models, fueled by experimental findings, to demonstrate that growth and remodeling have different effects on heart val...

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Detalles Bibliográficos
Autores principales: Oomen, Pim J. A., Holland, Maria A., Bouten, Carlijn V. C., Kuhl, Ellen, Loerakker, Sandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775310/
https://www.ncbi.nlm.nih.gov/pubmed/29352179
http://dx.doi.org/10.1038/s41598-018-19777-1