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Hemoglobin catalyzes CoA degradation and thiol addition to flavonoids

In the presence of CoA, cell-free extracts prepared from porcine liver was found to convert 7,8-dihydroxyflavone (DHF) to a pantetheine conjugate, which was a novel flavonoid. We purified a 7,8-DHF-converting enzyme from the extracts, and identified it as hemoglobin (Hb). The purified Hb showed the...

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Detalles Bibliográficos
Autores principales: Nagakubo, Toshiki, Kumano, Takuto, Hashimoto, Yoshiteru, Kobayashi, Michihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775311/
https://www.ncbi.nlm.nih.gov/pubmed/29352172
http://dx.doi.org/10.1038/s41598-018-19585-7