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Role of METTL20 in regulating β-oxidation and heat production in mice under fasting or ketogenic conditions

METTL20 is a seven-β-strand methyltransferase that is localised to the mitochondria and tri-methylates the electron transfer flavoprotein (ETF) β subunit (ETFB) at lysines 200 and 203. It has been shown that METTL20 decreases the ability of ETF to extract electrons from medium-chain acyl-coenzyme A...

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Detalles Bibliográficos
Autores principales: Shimazu, Tadahiro, Furuse, Tamio, Balan, Shabeesh, Yamada, Ikuko, Okuno, Shuzo, Iwanari, Hiroko, Suzuki, Takehiro, Hamakubo, Takao, Dohmae, Naoshi, Yoshikawa, Takeo, Wakana, Shigeharu, Shinkai, Yoichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775328/
https://www.ncbi.nlm.nih.gov/pubmed/29352221
http://dx.doi.org/10.1038/s41598-018-19615-4