Robust phenotype prediction from gene expression data using differential shrinkage of co-regulated genes

Discovery of robust diagnostic or prognostic biomarkers is a key to optimizing therapeutic benefit for select patient cohorts - an idea commonly referred to as precision medicine. Most discovery studies to derive such markers from high-dimensional transcriptomics datasets are weakly powered with sam...

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Detalles Bibliográficos
Autores principales: Zarringhalam, Kourosh, Degras, David, Brockel, Christoph, Ziemek, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775343/
https://www.ncbi.nlm.nih.gov/pubmed/29352257
http://dx.doi.org/10.1038/s41598-018-19635-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775343/
https://www.ncbi.nlm.nih.gov/pubmed/29352257
http://dx.doi.org/10.1038/s41598-018-19635-0

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