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Robust phenotype prediction from gene expression data using differential shrinkage of co-regulated genes
Discovery of robust diagnostic or prognostic biomarkers is a key to optimizing therapeutic benefit for select patient cohorts - an idea commonly referred to as precision medicine. Most discovery studies to derive such markers from high-dimensional transcriptomics datasets are weakly powered with sam...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775343/ https://www.ncbi.nlm.nih.gov/pubmed/29352257 http://dx.doi.org/10.1038/s41598-018-19635-0 |