Specificity of inhibitory KIRs enables NK cells to detect changes in an altered peptide environment

The activity of natural killer (NK) cells is tightly regulated by inhibitory and activating receptors. Inhibitory killer immunoglobulin-like receptors (iKIRs) survey the surface of target cells by monitoring the expression of human leukocyte antigen (HLA) class I. The binding of iKIRs has been shown...

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Detalles Bibliográficos
Autores principales: Carrillo-Bustamante, Paola, de Boer, Rob J., Keşmir, Can
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775373/
https://www.ncbi.nlm.nih.gov/pubmed/28695292
http://dx.doi.org/10.1007/s00251-017-1019-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775373/
https://www.ncbi.nlm.nih.gov/pubmed/28695292
http://dx.doi.org/10.1007/s00251-017-1019-1

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