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Soluble P-selectin promotes retinal ganglion cell survival through activation of Nrf2 signaling after ischemia injury

Retinal ischemic injuries play an important role in the pathogenesis of several eye disorders. Inflammation and oxidative stress are key players in ischemic injuries. Following retinal ischemia, vascular endothelial cells and leukocytes express several inflammatory adhesion receptors, such as select...

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Detalles Bibliográficos
Autores principales: Kapupara, Kishan, Wen, Yao-Tseng, Tsai, Rong-Kung, Huang, Shun-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775414/
https://www.ncbi.nlm.nih.gov/pubmed/29144506
http://dx.doi.org/10.1038/cddis.2017.566