LY2087101 and dFBr share transmembrane binding sites in the (α4)3(β2)2 Nicotinic Acetylcholine Receptor

Positive allosteric modulators (PAMs) of nicotinic acetylcholine receptors (nAChRs) have potential therapeutic application in neuropathologies associated with decrease in function or loss of nAChRs. In this study, we characterize the pharmacological interactions of the nAChRs PAM, LY2087101, with th...

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Detalles Bibliográficos
Autores principales: Deba, Farah, Ali, Hamed I., Tairu, Abisola, Ramos, Kara, Ali, Jihad, Hamouda, Ayman K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775429/
https://www.ncbi.nlm.nih.gov/pubmed/29352227
http://dx.doi.org/10.1038/s41598-018-19790-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775429/
https://www.ncbi.nlm.nih.gov/pubmed/29352227
http://dx.doi.org/10.1038/s41598-018-19790-4

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