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Esrrb Complementation Rescues Development of Nanog-Null Germ Cells

The transcription factors (TFs) Nanog and Esrrb play important roles in embryonic stem cells (ESCs) and during primordial germ-cell (PGC) development. Esrrb is a positively regulated direct target of NANOG in ESCs that can substitute qualitatively for Nanog function in ESCs. Whether this functional...

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Detalles Bibliográficos
Autores principales: Zhang, Man, Leitch, Harry G., Tang, Walfred W.C., Festuccia, Nicola, Hall-Ponsele, Elisa, Nichols, Jennifer, Surani, M. Azim, Smith, Austin, Chambers, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775501/
https://www.ncbi.nlm.nih.gov/pubmed/29320730
http://dx.doi.org/10.1016/j.celrep.2017.12.060