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Esrrb Complementation Rescues Development of Nanog-Null Germ Cells
The transcription factors (TFs) Nanog and Esrrb play important roles in embryonic stem cells (ESCs) and during primordial germ-cell (PGC) development. Esrrb is a positively regulated direct target of NANOG in ESCs that can substitute qualitatively for Nanog function in ESCs. Whether this functional...
Autores principales: | Zhang, Man, Leitch, Harry G., Tang, Walfred W.C., Festuccia, Nicola, Hall-Ponsele, Elisa, Nichols, Jennifer, Surani, M. Azim, Smith, Austin, Chambers, Ian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775501/ https://www.ncbi.nlm.nih.gov/pubmed/29320730 http://dx.doi.org/10.1016/j.celrep.2017.12.060 |
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