The RNA Polymerase II Factor RPAP1 Is Critical for Mediator-Driven Transcription and Cell Identity

The RNA polymerase II-associated protein 1 (RPAP1) is conserved across metazoa and required for stem cell differentiation in plants; however, very little is known about its mechanism of action or its role in mammalian cells. Here, we report that RPAP1 is essential for the expression of cell identity...

Descripción completa

Detalles Bibliográficos
Autores principales: Lynch, Cian J., Bernad, Raquel, Calvo, Isabel, Nóbrega-Pereira, Sandrina, Ruiz, Sergio, Ibarz, Nuria, Martinez-Val, Ana, Graña-Castro, Osvaldo, Gómez-López, Gonzalo, Andrés-León, Eduardo, Espinosa Angarica, Vladimir, del Sol, Antonio, Ortega, Sagrario, Fernandez-Capetillo, Oscar, Rojo, Enrique, Munoz, Javier, Serrano, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775503/
https://www.ncbi.nlm.nih.gov/pubmed/29320736
http://dx.doi.org/10.1016/j.celrep.2017.12.062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775503/
https://www.ncbi.nlm.nih.gov/pubmed/29320736
http://dx.doi.org/10.1016/j.celrep.2017.12.062

Ejemplares similares