The RNA Polymerase II Factor RPAP1 Is Critical for Mediator-Driven Transcription and Cell Identity

The RNA polymerase II-associated protein 1 (RPAP1) is conserved across metazoa and required for stem cell differentiation in plants; however, very little is known about its mechanism of action or its role in mammalian cells. Here, we report that RPAP1 is essential for the expression of cell identity...

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Detalles Bibliográficos
Autores principales: Lynch, Cian J., Bernad, Raquel, Calvo, Isabel, Nóbrega-Pereira, Sandrina, Ruiz, Sergio, Ibarz, Nuria, Martinez-Val, Ana, Graña-Castro, Osvaldo, Gómez-López, Gonzalo, Andrés-León, Eduardo, Espinosa Angarica, Vladimir, del Sol, Antonio, Ortega, Sagrario, Fernandez-Capetillo, Oscar, Rojo, Enrique, Munoz, Javier, Serrano, Manuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775503/
https://www.ncbi.nlm.nih.gov/pubmed/29320736
http://dx.doi.org/10.1016/j.celrep.2017.12.062

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