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Durable Interactions of T Cells with T Cell Receptor Stimuli in the Absence of a Stable Immunological Synapse

T cells engage in two modes of interaction with antigen-presenting surfaces: stable synapses and motile kinapses. Although it is surmised that durable interactions of T cells with antigen-presenting cells involve synapses, in situ 3D imaging cannot resolve the mode of interaction. We have establishe...

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Detalles Bibliográficos
Autores principales: Mayya, Viveka, Judokusumo, Edward, Abu Shah, Enas, Peel, Christopher G., Neiswanger, Willie, Depoil, David, Blair, David A., Wiggins, Chris H., Kam, Lance C., Dustin, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775504/
https://www.ncbi.nlm.nih.gov/pubmed/29320731
http://dx.doi.org/10.1016/j.celrep.2017.12.052