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Knockdown of Phospholipase Cɛ (PLCɛ) Inhibits Cell Proliferation via Phosphatase and Tensin Homolog Deleted on Chromosome 10 (PTEN)/AKT Signaling Pathway in Human Prostate Cancer

BACKGROUND: Phospholipase Cɛ (PLCɛ), a member of the plc family, has been extensively studied to reveal its role in the regulation of different cell functions, but understanding of the underlying mechanisms remains limited. In the present study, we explored the effects of PLCɛ on PTEN (phosphatase a...

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Detalles Bibliográficos
Autores principales: Wang, Xiao, Fan, Yanru, Du, Zhongbo, Fan, Jiaxin, Hao, Yanni, Wang, Jinhua, Wu, Xiaohou, Luo, Chunli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775730/
https://www.ncbi.nlm.nih.gov/pubmed/29330357
http://dx.doi.org/10.12659/MSM.908109