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Expression of Siglec-E Alters the Proteome of Lipopolysaccharide (LPS)-Activated Macrophages but Does Not Affect LPS-Driven Cytokine Production or Toll-Like Receptor 4 Endocytosis

Siglec-E is a murine CD33-related siglec that functions as an inhibitory receptor and is expressed mainly on neutrophils and macrophage populations. Recent studies have suggested that siglec-E is an important negative regulator of lipopolysaccharide (LPS)-toll-like receptor 4 (TLR4) signaling and on...

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Detalles Bibliográficos
Autores principales: Nagala, Manjula, McKenzie, Emma, Richards, Hannah, Sharma, Ritu, Thomson, Sarah, Mastroeni, Pietro, Crocker, Paul R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775731/
https://www.ncbi.nlm.nih.gov/pubmed/29379501
http://dx.doi.org/10.3389/fimmu.2017.01926