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Expression of Siglec-E Alters the Proteome of Lipopolysaccharide (LPS)-Activated Macrophages but Does Not Affect LPS-Driven Cytokine Production or Toll-Like Receptor 4 Endocytosis
Siglec-E is a murine CD33-related siglec that functions as an inhibitory receptor and is expressed mainly on neutrophils and macrophage populations. Recent studies have suggested that siglec-E is an important negative regulator of lipopolysaccharide (LPS)-toll-like receptor 4 (TLR4) signaling and on...
Autores principales: | Nagala, Manjula, McKenzie, Emma, Richards, Hannah, Sharma, Ritu, Thomson, Sarah, Mastroeni, Pietro, Crocker, Paul R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775731/ https://www.ncbi.nlm.nih.gov/pubmed/29379501 http://dx.doi.org/10.3389/fimmu.2017.01926 |
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