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ErbB4 signaling in dopaminergic axonal projections increases extracellular dopamine levels and regulates spatial/working memory behaviors

Genetic variants of Neuregulin 1 (NRG1) and its neuronal tyrosine kinase receptor ErbB4 are associated with risk for schizophrenia, a neurodevelopmental disorder characterized by excitatory/inhibitory imbalance and dopamine (DA) dysfunction. To date, most ErbB4 studies have focused on GABAergic inte...

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Detalles Bibliográficos
Autores principales: Skirzewski, M, Karavanova, I, Shamir, A, Erben, L, Garcia-Olivares, J, Shin, J H, Vullhorst, D, Alvarez, V A, Amara, S G, Buonanno, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5775946/
https://www.ncbi.nlm.nih.gov/pubmed/28727685
http://dx.doi.org/10.1038/mp.2017.132