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Salmonella Typhi Bactericidal Antibodies Reduce Disease Severity but Do Not Protect against Typhoid Fever in a Controlled Human Infection Model

Effective vaccines against Salmonella Typhi, a major cause of febrile illness in tropical regions, can have a significant effect as a disease control measure. Earlier work has shown that immunization with either of two Salmonella Typhi vaccines, licensed Ty21a or candidate M01ZH09, did not provide f...

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Detalles Bibliográficos
Autores principales: Juel, Helene B., Thomaides-Brears, Helena B., Darton, Thomas C., Jones, Claire, Jones, Elizabeth, Shrestha, Sonu, Sie, Rebecca, Eustace, Andrew, Galal, Ushma, Kurupati, Prathiba, Van, Tan T., Thieu, Nga T. V., Baker, Stephen, Blohmke, Christoph J., Pollard, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776093/
https://www.ncbi.nlm.nih.gov/pubmed/29387052
http://dx.doi.org/10.3389/fimmu.2017.01916